OverviewHyperbaric oxygen therapy (HBOT) is theinhalation of 100 percent oxygen inside ahyperbaric chamber that is pressurized to greaterthan 1 atmosphere (atm). HBOT causes bothmechanical and physiologic effects by inducing astate of increasedMoreOverviewHyperbaric oxygen therapy (HBOT) is theinhalation of 100 percent oxygen inside ahyperbaric chamber that is pressurized to greaterthan 1 atmosphere (atm). HBOT causes bothmechanical and physiologic effects by inducing astate of increased pressure and hyperoxia. HBOTis typically administered at 1 to 3 atm. While theduration of an HBOT session is typically 90 to120 minutes, the duration, frequency, andcumulative number of sessions have not beenstandardized.HBOT is administered in two primary ways,using a monoplace chamber or a multiplacechamber.
The monoplace chamber is the lesscostlyoption for initial setup and operation butprovides less opportunity for patient interactionwhile in the chamber. Multiplace chambers allowmedical personnel to work in the chamber andcare for acute patients to some extent.
The entiremultiplace chamber is pressurized, so medicalpersonnel may require a controlled decompression,depending on how long they were exposed to thehyperbaric air environment.The purpose of this report is to provide a guideto the strengths and limitations of the evidenceabout the use of HBOT to treat patients who havebrain injury, cerebral palsy, and stroke. Braininjury can be caused by an external physical force(also known as traumatic brain injury, or TBI)-rapid acceleration or deceleration of the head-bleeding within or around the brain- lack ofsufficient oxygen to the brain- or toxic substancespassing through the blood-brain barrier.
Braininjury results in temporary or permanentimpairment of cognitive, emotional, and/orphysical functioning. Cerebral palsy refers to amotor deficit that usually manifests itself by 2years of age and is secondary to an abnormality ofat least the part of the brain that relates to motorfunction. Stroke refers to a sudden interruption ofthe blood supply to the brain, usually caused by ablocked artery or a ruptured blood vessel, leadingto an interruption of homeostasis of cells, andsymptoms such as loss of speech and loss of motorfunction.